- ZFPM2-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH 46,XY sex reversal 3; 46,XY sex reversal 9; Diaphragmatic Hernia 3; INTERACTS WITH aristolochic acid A; cadmium dichloride; Didecyldimethylammonium
- Sry3a [Search on AGR]
Rattus norvegicus Predicted to enable calmodulin binding activity. Predicted to be involved in sex differentiation. Predicted to be located in nuclear speck. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY complete gonadal dysgenesis; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y).
- Rsxr [Search on AGR]
Mus musculus PHENOTYPE: The Rsxr<sup>129S1/Sv</sup> allele confers resistance to sex reversal in genetic XY males from consomic line B6.129-Chr Y<sup>POS</sup>. The Rsxr<sup>C57BL/6J</sup> allele confers sex reversal in genetic XY males from consomic line C57BL/6J-Hba<sup>th-J</sup> Chr Y<sup>POS</sup>. [provided by MGI curators]
- Dhh [Search on AGR]
Rattus norvegicus Predicted to enable calcium ion binding activity; patched binding activity; and zinc ion binding activity. Involved in several processes, including response to estradiol; response to estrogen; and spermatid development. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in 46,XY complete gonadal dysgenesis; 46,XY gonadal dysgenesis with minifascicular neuropathy; and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3-bis(4-hydroxyphenyl)propionitrile.
- t [Search on AGR]
Mus musculus PHENOTYPE: Homozygous mice die during embryonic development. Heterozygous mice have skeletal abnormalities. On specific genetic backgrounds, some alleles cause partial or complete sex-reversal of chromosomally XY mice. [provided by MGI curators]
- Sry [Search on AGR]
Mus musculus PHENOTYPE: Variations in expression of alleles on specific backgrounds result in partial and/or complete male to female sex reversal. Deletion of alleles results in XY females. [provided by MGI curators]
- Sry [Search on AGR]
Rattus norvegicus Enables enzyme binding activity and sequence-specific DNA binding activity. Involved in male sex determination and positive regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY complete gonadal dysgenesis; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y); INTERACTS WITH ammonium chloride; bisphenol A; copper atom.
- Cul4a [Search on AGR]
Homo sapiens CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]
- Hsf5 [Search on AGR]
Homo sapiens Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in XY body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
- rha-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity and helicase activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in 46,XY sex reversal. Is an ortholog of human DHX37 (DEAH-box helicase 37).