lin-15

Caenorhabditis elegans

lin-15A

Caenorhabditis elegans

Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad.

lin-52

Caenorhabditis elegans

Involved in embryo development; negative regulation of signal transduction; and regulation of multicellular organismal development. Part of DRM complex. Expressed in AS neuron; anal depressor muscle; chemosensory neurons; excretory cell; and intestine. Is an ortholog of human LIN52 (lin-52 DREAM MuvB core complex component).

F38H4.16

Caenorhabditis elegans

Is affected by lin-14 and lin-4 based on microarray studies.

T12B5.18

Caenorhabditis elegans

Is affected by sir-2.1; lin-14; and lin-4 based on microarray studies.

lin-53

Caenorhabditis elegans

Enables histone deacetylase binding activity. Involved in several processes, including embryonic digestive tract morphogenesis; negative regulation of vulval development; and nematode male tail tip morphogenesis. Acts upstream of or within mitochondrial unfolded protein response. Located in nucleus. Part of DRM complex and NuRD complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human RBBP4 (RB binding protein 4, chromatin remodeling factor) and RBBP7 (RB binding protein 7, chromatin remodeling factor).

suv-2

Caenorhabditis elegans

lin-65

Caenorhabditis elegans

Involved in chromatin remodeling and mitochondrial unfolded protein response. Located in cytosol and nucleus. Expressed in head neurons and intestine.

F39E9.19

Caenorhabditis elegans

Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.

F39E9.25

Caenorhabditis elegans

Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.