- kin-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity. Involved in feeding behavior; regulation of meiosis I; and regulation of nematode pharyngeal pumping. Located in cell cortex. Expressed in several structures, including alimentary muscle; excretory cell; intestine; nerve ring; and pharyngeal-intestinal valve. Is an ortholog of human TAOK1 (TAO kinase 1); TAOK2 (TAO kinase 2); and TAOK3 (TAO kinase 3).
- Tao [Search on AGR]
Drosophila melanogaster Tao (Tao) encodes a Ser/Thr kinase belonging to the Mst/Ste20 family. It is implicated in the Hippo and PAR-1 pathways. It contributes to restriction of tissue growth during development, regulation of microtubule dynamics, neuronal polarity, neural development, ethanol-stimulated behavioral response, and apoptosis.
- Ly31 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on T- and B-lymphocytes. The a allele determines presence of Ly31.1 in A/He, AKR, BALB/c, C3H/He, DBA/2, SWR; the b allele determines absence in C57BL, DBA/1, SM, 129. Ly31.1 antigen was shown to be an alkaline phosphatase. [provided by MGI curators]
- Ly34 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on T-cells and in brain, liver and kidney. The b allele determines antigen presence in C58, C3H/He, DBA/2, NZB, P, CE and C57 strains; the a allele determines absence in C57BLKS, A/He, AKR, CBA/J, DBA/1, BALB/c, HRS and STS. [provided by MGI curators]
- Sas2 [Search on AGR]
Mus musculus PHENOTYPE: Sas2 controls an antigen seen in reciprocal immunization of BALB/c and MOL/ANJ. The a allele determines antigen specificity in most inbreds, e.g., A/He, AKR, BALB/c, C3H/He, C57BL/6, DBA/2, NZB; the b allele determines specificity in M.m. molossinus derived strains. Heterozygotes have both antigens. [provided by MGI curators]
- Epa1 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls presence or absence of an epidermal antigen inducing CTL in H2 compatible hosts lacking the antigen. Antigen is present in AKR, BALB/c, CBA/J, C3H/Bi, C57BL and DBA; and absent in C3H/He, C3H/An, A/J, A/He, LG and ST/b. This locus also acts like a minor histocompatibility locus. [provided by MGI curators]
- Schip1 [Search on AGR]
Drosophila melanogaster Schwannomin interacting protein 1 (Schip1) encodes a protein that is involved in negative regulation of organ growth by promoting the Hippo signaling pathway. It binds to the products of ex and Tao, activating the phosphorylation of the kinase encoded by hpo.
- Tpe1 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls electrophoretic variation of a protein in tears. A co-dominant fast band is seen in C3H/He, CBA/N, IC/Le, KK, SWM/MS, WB/Re and WC/Re; a co-dominant slow band in DBA/1, DBA/2, C57L, NZB, NZW and SM; and a recessive null allele (no band) in BALB/c, A/He, AKR, CL/Fr, DDD and NC. [provided by MGI curators]
- Taok2 [Search on AGR]
Rattus norvegicus Enables ATP binding activity and MAP kinase kinase kinase activity. Involved in MAPK cascade; basal dendrite arborization; and regulation of synapse organization. Is active in glutamatergic synapse and postsynapse. Orthologous to human TAOK2 (TAO kinase 2); PARTICIPATES IN
p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
- Kth1 [Search on AGR]
Mus musculus PHENOTYPE: The a allele occurs in most inbred strains and determines a protein of pI 5.5. The o allele (absence of protein) is found in AKR/J and C3H/He. [provided by MGI curators]