- ZFPM2-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH 46,XY sex reversal 3; 46,XY sex reversal 9; Diaphragmatic Hernia 3; INTERACTS WITH aristolochic acid A; cadmium dichloride; Didecyldimethylammonium
- Sry3a [Search on AGR]
Rattus norvegicus Predicted to enable calmodulin binding activity. Predicted to be involved in sex differentiation. Predicted to be located in nuclear speck. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY complete gonadal dysgenesis; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y).
- Rsxr [Search on AGR]
Mus musculus PHENOTYPE: The Rsxr<sup>129S1/Sv</sup> allele confers resistance to sex reversal in genetic XY males from consomic line B6.129-Chr Y<sup>POS</sup>. The Rsxr<sup>C57BL/6J</sup> allele confers sex reversal in genetic XY males from consomic line C57BL/6J-Hba<sup>th-J</sup> Chr Y<sup>POS</sup>. [provided by MGI curators]
- Ly31 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on T- and B-lymphocytes. The a allele determines presence of Ly31.1 in A/He, AKR, BALB/c, C3H/He, DBA/2, SWR; the b allele determines absence in C57BL, DBA/1, SM, 129. Ly31.1 antigen was shown to be an alkaline phosphatase. [provided by MGI curators]
- Ly34 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen on T-cells and in brain, liver and kidney. The b allele determines antigen presence in C58, C3H/He, DBA/2, NZB, P, CE and C57 strains; the a allele determines absence in C57BLKS, A/He, AKR, CBA/J, DBA/1, BALB/c, HRS and STS. [provided by MGI curators]
- Dhh [Search on AGR]
Rattus norvegicus Predicted to enable calcium ion binding activity; patched binding activity; and zinc ion binding activity. Involved in several processes, including response to estradiol; response to estrogen; and spermatid development. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in 46,XY complete gonadal dysgenesis; 46,XY gonadal dysgenesis with minifascicular neuropathy; and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3-bis(4-hydroxyphenyl)propionitrile.
- Sas2 [Search on AGR]
Mus musculus PHENOTYPE: Sas2 controls an antigen seen in reciprocal immunization of BALB/c and MOL/ANJ. The a allele determines antigen specificity in most inbreds, e.g., A/He, AKR, BALB/c, C3H/He, C57BL/6, DBA/2, NZB; the b allele determines specificity in M.m. molossinus derived strains. Heterozygotes have both antigens. [provided by MGI curators]
- Epa1 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls presence or absence of an epidermal antigen inducing CTL in H2 compatible hosts lacking the antigen. Antigen is present in AKR, BALB/c, CBA/J, C3H/Bi, C57BL and DBA; and absent in C3H/He, C3H/An, A/J, A/He, LG and ST/b. This locus also acts like a minor histocompatibility locus. [provided by MGI curators]
- t [Search on AGR]
Mus musculus PHENOTYPE: Homozygous mice die during embryonic development. Heterozygous mice have skeletal abnormalities. On specific genetic backgrounds, some alleles cause partial or complete sex-reversal of chromosomally XY mice. [provided by MGI curators]
- Sry [Search on AGR]
Mus musculus PHENOTYPE: Variations in expression of alleles on specific backgrounds result in partial and/or complete male to female sex reversal. Deletion of alleles results in XY females. [provided by MGI curators]