- MF(ALPHA)1 [Search on AGR]
Saccharomyces cerevisiae Alpha-factor mating pheromone made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor; binds copper(II) ions
- Mf [Search on AGR]
Drosophila melanogaster Myofilin (Mf) encodes a structural protein of muscular thick filaments, which may be needed for filament assembly. Alternative splicing of the gene, controlled by the product of salm, produces isoforms of varying size in thoracic muscles.
- MF(ALPHA)2 [Search on AGR]
Saccharomyces cerevisiae Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed; binds copper(II) ions
- Mdfi [Search on AGR]
Homo sapiens This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]
- URE2 [Search on AGR]
Saccharomyces cerevisiae Nitrogen catabolite repression transcriptional regulator; inhibits GLN3 transcription in good nitrogen source; role in sequestering Gln3p and Gat1p to the cytoplasm; has glutathione peroxidase activity and can mutate to acquire GST activity; self-assembly under limited nitrogen conditions creates [URE3] prion and releases catabolite repression
- Klk9 [Search on AGR]
Homo sapiens The protein encoded by this gene is a kallikrein-related serine protease. This gene is activated by steroid hormones in a human breast cancer cell line, making it a good marker for cancer detection. The encoded protein is found primarily in the cytoplasm.[provided by RefSeq, Oct 2010]
- Pp [Search on AGR]
Mus musculus PHENOTYPE: This locus controls part of passive avoidance learning, where mice are trained to avoid foot shock by remaining on a shelf. The dominant b allele determines poor passive avoidance learning in C57BL/6J; the recessive d allele determines good passive avoidance learning in DBA/2J. [provided by MGI curators]
- CTAG1A [Search on AGR]
Homo sapiens The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome. [provided by RefSeq, Dec 2015]
- Guk1 [Search on AGR]
Homo sapiens The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
- Hspa4l [Search on AGR]
Homo sapiens The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]