Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Located in nucleus. Part of nucleosome. Expressed in several structures, including germ cell; somatic cell; and in male. Human ortholog(s) of this gene implicated in Bryant-Li-Bhoj neurodevelopmental syndrome 1 and Bryant-Li-Bhoj neurodevelopmental syndrome 2. Is an ortholog of human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B).
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in several structures, including somatic cell. Human ortholog(s) of this gene implicated in Bryant-Li-Bhoj neurodevelopmental syndrome 1 and Bryant-Li-Bhoj neurodevelopmental syndrome 2. Is an ortholog of human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B).
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Expressed in germline blastomere. Human ortholog(s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple); and germ cell cancer (multiple). Is an ortholog of human CHEK2 (checkpoint kinase 2).
Predicted to enable nuclease activity. Predicted to be involved in interstrand cross-link repair. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.
Predicted to enable hydrolase activity, acting on ester bonds and nucleic acid binding activity. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.
Predicted to enable nuclease activity and nucleic acid binding activity. Predicted to be involved in interstrand cross-link repair. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.
Predicted to enable nuclease activity and nucleic acid binding activity. Predicted to be involved in interstrand cross-link repair. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.
Predicted to enable nuclease activity and nucleic acid binding activity. Predicted to be involved in interstrand cross-link repair. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.
Predicted to enable nuclease activity and nucleic acid binding activity. Predicted to be involved in interstrand cross-link repair. Is an ortholog of C. elegans fan-1. In C. elegans, fan-1 is involved in DNA repair.