PPA39683

Pristionchus pacificus

Is predicted to encode a protein with the following domains: De-etiolated protein 1, Det1 and De-etiolated protein 1 Det1.

adss-1

Caenorhabditis elegans

Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1).

paic-1

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

OVOC833

Onchocerca volvulus

Is predicted to encode a protein with the following domains: De-etiolated protein 1, Det1 and De-etiolated protein 1 Det1. Is an ortholog of B. malayi Bm12912.

Bm12912

Brugia malayi

Is predicted to encode a protein with the following domains: De-etiolated protein 1, Det1 and De-etiolated protein 1 Det1. Is an ortholog of O. volvulus OVOC833.

Gpat4

Drosophila melanogaster

Glycerol-3-phosphate acyltransferase 4 (Gpat4) encodes a de novo synthase of lysophosphatidic acid.

ADE8

Saccharomyces cerevisiae

Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway

ADE6

Saccharomyces cerevisiae

Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway

tdo-2

Caenorhabditis elegans

Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).

Y52B11A.11

Caenorhabditis elegans

Enriched in ABplpppppp; ABprpppppp; AVG; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including swsn-2.2; nuo-6; and mut-16 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: DE-cadherin, Ig-like domain.