ace-3

Caenorhabditis elegans

Enables acetylcholinesterase activity and protein homodimerization activity. Involved in several processes, including acetylcholine catabolic process; hatching; and regulation of backward locomotion. Predicted to be located in extracellular space and plasma membrane. Expressed in body wall musculature; neurons; pharyngeal muscle cell; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and drug dependence (multiple). Is an ortholog of human ACHE (acetylcholinesterase (Yt blood group)) and BCHE (butyrylcholinesterase).

ace-1

Caenorhabditis elegans

Enables acetylcholinesterase activity and identical protein binding activity. Involved in acetylcholine catabolic process and regulation of locomotion. Located in extracellular space. Expressed in CEP; M cell; OLL; body wall musculature; and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and drug dependence (multiple). Is an ortholog of human ACHE (acetylcholinesterase (Yt blood group)) and BCHE (butyrylcholinesterase).

unc-123

Caenorhabditis elegans

ilys-4

Caenorhabditis elegans

Predicted to enable lysozyme activity. Predicted to be involved in defense response to bacterium and killing of cells of another organism. Expressed in DD neuron and neurons.

srpr-1.1

Caenorhabditis elegans

Enriched in DD neuron based on microarray studies. Is affected by several genes including etr-1; spr-5; and pmt-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and single-walled carbon nanotube based on RNA-seq and microarray studies.

nspg-7.2

Caenorhabditis elegans

Enriched in DD neuron; intestine; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including hyl-2; swsn-1; and nuo-6 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including tryptophan; Tunicamycin; and TPEN based on microarray and RNA-seq studies.

fam-1

Caenorhabditis elegans

twk-30

Caenorhabditis elegans

Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in DD neuron; motor neurons; neurons; and ventral cord neurons.

T23F11.2

Caenorhabditis elegans

Enriched in several structures, including AVK; DD neuron; germ line; pharyngeal-intestinal valve cell; and sperm based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including numr-2; numr-1; and mut-16 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-eight chemicals including ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq; microarray; and proteomic studies.

R106.8

Caenorhabditis elegans

Enriched in DD neuron and neurons based on microarray studies. Is affected by several genes including nuo-6; etr-1; and isp-1 based on RNA-seq and microarray studies. Is affected by four chemicals including quercetin; Hydrolyzable Tannins; and Sirolimus based on microarray studies.