gcna-1

Caenorhabditis elegans

Enables SUMO polymer binding activity. Involved in meiotic chromosome segregation and protein-DNA covalent cross-linking repair. Located in PML body and condensed chromosome. Expressed in Z2; Z3; and germ cell. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 4. Is an ortholog of human GCNA (germ cell nuclear acidic peptidase).

Hmces

Homo sapiens

Enables DNA-(abasic site) binding activity; protein-DNA covalent cross-linking activity; and single-stranded DNA binding activity. Involved in interstrand cross-link repair; protein-DNA covalent cross-linking repair; and somatic hypermutation of immunoglobulin genes. Is active in replication fork. [provided by Alliance of Genome Resources, Apr 2025]

ule-1

Caenorhabditis elegans

Predicted to enable chitin binding activity. Predicted to be located in extracellular region.

SRAE_2000279300

Strongyloides ratti

Predicted to enable nuclease activity. Predicted to be involved in interstrand cross-link repair.

PPA37871

Pristionchus pacificus

Predicted to enable nuclease activity. Predicted to be involved in interstrand cross-link repair.

Xrcc2

Drosophila melanogaster

X-ray repair cross complementing 2 (Xrcc2) encodes a protein involved in DNA repair.

Bm8405

Brugia malayi

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking.

OVOC1308

Onchocerca volvulus

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking.

OVOC1307

Onchocerca volvulus

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking.

pqn-74

Caenorhabditis elegans

Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region.