Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in regulation of cell migration and regulation of egg-laying behavior. Located in extracellular space. Expressed in several structures, including M4 neuron; P5.p; P7.p; male-specific anatomical entity; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); hypogonadotropic hypogonadism (multiple); and prostate disease (multiple). Is an ortholog of human FGF18 (fibroblast growth factor 18) and FGF8 (fibroblast growth factor 8).
Enables protein kinase activity. Involved in several processes, including egg-laying behavior; muscle cell cellular homeostasis; and nematode larval development. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in head neurons; hypodermis; intestine; male sex myoblast; and vulval muscle. Used to study bone disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bone disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human FGFR2 (fibroblast growth factor receptor 2).
Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in cytoplasm. Predicted to be part of heterotrimeric G-protein complex.
Enables polynucleotide 5'-phosphatase activity. Involved in polynucleotide 5' dephosphorylation and positive regulation of gene expression. Located in nucleus. Expressed in tail. Is an ortholog of human RNGTT (RNA guanylyltransferase and 5'-phosphatase).
Predicted to enable glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Is an ortholog of human B3GALT1 (beta-1,3-galactosyltransferase 1).
Predicted to enable G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and egg-laying behavior. Predicted to be located in axon; membrane; and somatodendritic compartment. Expressed in HSNL; HSNR; PVQL; PVQR; and vulva.