rgs-3

Caenorhabditis elegans

Involved in chemosensory behavior and sensory perception of bitter taste. Expressed in amphid neurons and phasmid neurons.

rgs-8.2

Caenorhabditis elegans

Enriched in Q cell based on RNA-seq studies. Is affected by several genes including cyc-1; swsn-1; and csr-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RGS, subdomain 2; RGS, subdomain 1/3; RGS domain superfamily; Regulator of G protein signaling domain; and RGS domain. Is an ortholog of human RGS1 (regulator of G protein signaling 1). Human RGS1 enables G-protein alpha-subunit binding activity and GTPase activator activity.

rgs-1

Caenorhabditis elegans

Enables GTPase activator activity. Involved in chemosensory behavior and sensory perception of bitter taste. Expressed in head; neurons; and tail. Is an ortholog of human RGS19 (regulator of G protein signaling 19).

rgs-4

Caenorhabditis elegans

Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including mter-4; etr-1; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RGS domain; RGS domain superfamily; RGS, subdomain 2; and Regulator of G protein signaling domain.

rgs-7

Caenorhabditis elegans

Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4).

rgs-5

Caenorhabditis elegans

Predicted to be involved in protein localization. Predicted to be located in mitochondrion and plasma membrane. Is an ortholog of human AKAP10 (A-kinase anchoring protein 10).

rgs-2

Caenorhabditis elegans

Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Expressed in head neurons; pharyngeal muscle cell; tail neurons; uterine muscle; and ventral cord neurons. Is an ortholog of human RGS19 (regulator of G protein signaling 19).

rgs-6

Caenorhabditis elegans

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Human ortholog(s) of this gene implicated in nephrolithiasis. Is an ortholog of human RGS14 (regulator of G protein signaling 14).

Y71G12B.10

Caenorhabditis elegans

Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Used to study 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Human ortholog(s) of this gene implicated in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).

ZK909.3

Caenorhabditis elegans

Predicted to enable guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity. Is an ortholog of human HDDC3 (HD domain containing 3).