H3f3b [Search on AGR]
Rattus norvegicus Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Predicted to be a structural constituent of chromatin. Involved in response to hormone. Predicted to be located in chromosome, telomeric region and nucleoplasm. Predicted to be part of nucleosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Bryant-Li-Bhoj neurodevelopmental syndrome 2. Orthologous to several human genes including H3-3B (H3.3 histone B); PARTICIPATES IN histone modification pathway; systemic lupus erythematosus pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-tert-Octylphenol.
H3f3a [Search on AGR]
Rattus norvegicus Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in nucleosome assembly; oocyte maturation; and positive regulation of cell growth. Predicted to act upstream of or within several processes, including constitutive heterochromatin formation; negative regulation of chromosome condensation; and osteoblast differentiation. Predicted to be located in Barr body; chromosome, telomeric region; and nucleoplasm. Predicted to be part of inner kinetochore and nucleosome. Predicted to be active in chromatin and chromosome, centromeric region. Human ortholog(s) of this gene implicated in Bryant-Li-Bhoj neurodevelopmental syndrome 1. Orthologous to several human genes including H3-3A (H3.3 histone A); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; fipronil.