Socs7

Homo sapiens

Predicted to enable phosphorylation-dependent protein binding activity; signaling adaptor activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in insulin receptor signaling pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of neuron migration. Predicted to act upstream of or within brain development; fat cell differentiation; and protein ubiquitination. Located in cytosol. Is active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

ash-2

Caenorhabditis elegans

Predicted to enable transcription cis-regulatory region binding activity. Involved in determination of adult lifespan; programmed cell death; and transdifferentiation. Located in nucleus. Part of MLL3/4 complex. Expressed in germ line. Is an ortholog of human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit).

T24C4.10

Caenorhabditis elegans

Is affected by ash-2 based on RNA-seq studies.

H04D03.7

Caenorhabditis elegans

Is affected by ash-2 based on RNA-seq studies.

R193.6

Caenorhabditis elegans

Is affected by ash-2 based on RNA-seq studies.

Y54F10BM.21

Caenorhabditis elegans

Is affected by ash-2 based on RNA-seq studies.

Y54F10BM.22

Caenorhabditis elegans

Is affected by ash-2 and hsf-1 based on RNA-seq studies.

F08F1.21

Caenorhabditis elegans

Is affected by unc-30; ash-2; and hsf-1 based on RNA-seq studies.

srh-210

Caenorhabditis elegans

Expressed in several structures, including ASH; head mesodermal cell; pharyngeal-intestinal valve; retrovesicular ganglion; and vulva.

anr-26

Caenorhabditis elegans

Is affected by daf-2; sin-3; and ash-2 based on microarray and RNA-seq studies.