Expr9342

lin-44 was mostly localized to the posterior half of L1 larvae, in a pattern that was already present at the comma stage of embryonic development. lin-44 transcripts were present in the tail hypodermal cells hyp8, hyp9, hyp10 and hyp11, and at later larval stages in the phasmid socket cells PHso1 and PHso2 as previously reported (Herman et al., 1995). In addition, it was found that lin-44 is expressed in the rectal epithelial cells B and Y, demonstrating that lin-44 has a more anterior expression domain than has been observed using reporter transgenes.

Expr11887

At the comma stage, during larval development, and in adult animals, mig-14 is mainly expressed in the posterior part of the animal. The expression of mig-14 overlaps with the known expression patterns of C. elegans Wnt genes. Thus, mig-14 is expressed in the tail hypodermis, which expresses the Wnt gene lin-44 (Herman and Horvitz, 1994); in cells in the anal region that express egl-20/Wnt (Whangbo and Kenyon, 1999); and in posterior body wall muscle cells that express cwn-1/Wnt (Gleason et al., 2006; Pan et al., 2006). In addition, mig-14 is strongly expressed in the stomatointestinal muscle, the mesoblast cell M and its descendants, the CAN neurons, the developing vulva, the pharynx, and the pharyngeal intestinal valve. mig-14 is also weakly expressed in a small subset of head neurons, the ventral nerve cord, and the seam cells, but is undetectable in the main body hypodermis and the intestine.