syndactyly type 5

A syndactyly characterized by postaxial syndactyly of the hands and feet associated with metacarpal and metatarsal fusion typically affecting the 4th and 5th or the 3rd and 4th digits that has_material_basis_in heterozygous mutation in the HOXD13 gene on chromosome 2q31.1.

Tietze's syndrome

A cartilage disease that is characterized by localized tenderness and non-suppurative swelling, typically associated with the 2nd or 3rd costal cartilages unilaterally caused by inflammation of one or more of the costal cartilages and that has symptom anterior chest pain.

Burkitt lymphoma

A mature B-cell neoplasm of B-cells found in the germinal center.

lambda 5 deficiency

A B cell deficiency that has_material_basis_in mutations in the IGLL1 gene. Lambda 5 mutations can cause a block in B cell development at the transition between the pro-B cell and the pre-B cell stage.

B-lymphoblastic leukemia/lymphoma with hypodiploidy

A B-lymphoblastic leukemia/lymphoma that is composed of B-lymphoblasts which contain less than 46 chromosomes.

splenic marginal zone lymphoma

A marginal zone B-cell lymphocyte located_in the spleen comprised of B-cells in place of white pulp.

diffuse large B-cell lymphoma

A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern.

B-lymphoblastic leukemia/lymphoma with hyperdiploidy

A B-lymphoblastic leukemia/lymphoma that is composed of B-lymphoblasts which contain more than 50 and usually less than 66 chromosomes.

primary mediastinal B-cell lymphoma

A large B-cell lymphoma that is is characterized by a diffuse proliferation of medium to large B-cells associated with sclerosis.

follicular lymphoma

A B-cell lymphoma that is characterized as an indolent non-Hodgkin's lymphoma and has_material_basis_in follicle center B-cells (centrocytes and centroblasts).