WBPaper00040471Is2

Caenorhabditis elegans

[PH20::(h)Mo-Rho9; PH20::DsRed]

WBPaper00040471Is5

Caenorhabditis elegans

[Pmyo-3::(h)Mo-Rho9; Pmyo-3::DsRed]

moc-6

Caenorhabditis elegans

Predicted to enable nucleotide binding activity. Predicted to contribute to molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Predicted to be part of molybdopterin adenylyltransferase complex and molybdopterin synthase complex.

moc-3

Caenorhabditis elegans

Predicted to enable URM1 activating enzyme activity; nucleotidyltransferase activity; and sulfurtransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process; protein urmylation; and tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Is an ortholog of human MOCS3 (molybdenum cofactor synthesis 3).

F49H6.5

Caenorhabditis elegans

Predicted to enable GTP 3',8'-cyclase activity and cyclic pyranopterin monophosphate synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Is an ortholog of human MOCS1 (molybdenum cofactor synthesis 1).

spe-17

Caenorhabditis elegans

Involved in spermatid development.

moc-5

Caenorhabditis elegans

Predicted to enable GTP 3',8'-cyclase activity and cyclic pyranopterin monophosphate synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Is an ortholog of human MOCS1 (molybdenum cofactor synthesis 1).

moc-1

Caenorhabditis elegans

Predicted to enable molybdopterin molybdotransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process and synapse organization. Predicted to be located in cytosol; dendrite; and postsynapse. Expressed in tail. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type C. Is an ortholog of human GPHN (gephyrin).

spe-5

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in intracellular pH reduction; positive regulation of programmed cell death; and spermatocyte division. Located in cytoplasm. Expressed in sperm and spermatocyte. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy and renal tubular acidosis. Is an ortholog of human ATP6V1B1 (ATPase H+ transporting V1 subunit B1) and ATP6V1B2 (ATPase H+ transporting V1 subunit B2).

nmrk-1

Caenorhabditis elegans

Predicted to enable molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Predicted to be part of molybdopterin synthase complex. Used to study molybdenum cofactor deficiency type B. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Is an ortholog of human MOCS2 (molybdenum cofactor synthesis 2).