gene: smc-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable double-stranded DNA binding activity. Involved in establishment of mitotic sister chromatid cohesion. Located in chromatin and nucleus. Part of MIS12/MIND type complex and cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Is an ortholog of human SMC3 (structural maintenance of chromosomes 3).