Enriched in digestive tract based on proteomic studies. Is predicted to encode a protein with the following domains: WD domain, G-beta repeat; PH-like domain superfamily; WD40/YVTN repeat-like-containing domain superfamily; WD40 repeat; PH-BEACH domain; BEACH domain superfamily; Beige/BEACH domain; PH domain associated with Beige/BEACH; BEACH domain; and WD40-repeat-containing domain superfamily. Is an ortholog of C. elegans
sel-2. In C. elegans,
sel-2 is involved in several processes, including apical protein localization; negative regulation of Notch signaling pathway; and regulation of vulval development.